I am what might politely be termed "directionally challenged." This means that, although I can read a map, I am usually lost, especially if someone's idea of giving directions is "go north two blocks and turn west." Say what? How would I know which way west is?
Thus when people tell me that they've driven into (to use joe's system of naming) Big City Like No Other or Windy City or the Land of the Bean and the Cod to see a show, an exhibit at the museum, etc., my impulse is more to ask "what route did you take?" and "where did you find a place to park?" than about the exhibit itself.
Due to frequent trips there, though, I can almost navigate around City Where Every Major Street Ends in a Bridge without getting too lost or without hurtling across a bridge into another city (and sometimes into another state). I would like to think this is because I know the streets, but after I took the wrong exit on a recent trip (i.e., not the one that Google Maps told me to take), I was able to get to the hotel by thinking to myself, "I must be close, because the trees look right." And I did get there, all because the trees looked right.
This doesn't bode well for taking up orienteering as a hobby, but did I ever feel as though I'd accomplished something once I got to my destination!